T4-DNA Ligase

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Object Details

user

Genentech, Inc.

Description (Brief)

This silver metal canister once contained T4-DNA ligase, an enzyme commonly used in molecular biology. T4-DNA ligase helps create bonds between the ends of fragments of DNA.

This capability makes it useful in the laboratory when scientists want to combine DNA from two different sources in order to create recombinant DNA. This particular canister of T4-DNA ligase was used to create recombinant DNA molecules at Genentech, a biotechnology company, in the early 1980s.

Source:

Aehle, W. (2007). Enzymes in industry: Production and applications. Wiley-VCH.

Location

Currently not on view

Credit Line

Gift of Genentech

date made

1984-08

ID Number

2012.0198.26

accession number

2012.0198

catalog number

2012.0198.26

Object Name

T4-DNA ligase

Physical Description

metal (overall material)

Measurements

overall: 2 13/16 in x 1 1/4 in; 7.14375 cm x 3.175 cm

place made

West Germany

used

United States: California, South San Francisco

See more items in

Medicine and Science: Biological Sciences

Biotechnology and Genetics

Science & Mathematics

Data Source

National Museum of American History

Metadata Usage

CC0

Link to Original Record

https://n2t.net/ark:/65665/ng49ca746ad-a806-704b-e053-15f76fa0b4fa

Record ID

nmah_1427286