Object Details
maker
Hoffmann-La Roche
Roche Laboratories
Description (Brief)
Roferon-A is an injectible, recombinant pharmaceutical used to treat different types of leukemia, malignant melanoma, multiple myeloma, non-Hodgkin's lymphoma, AIDS-related sarcoma, and hepatitis. It was discontinued in October 2007, as new therapies for the diseases it treated were developed.
Recombinant pharmaceuticals are created by inserting genes from one species into a host species, often yeast or bacteria, where they do not naturally occur. The genes code for a desired product, and therefore the genetically modified host organisms can be grown and used as a kind of living factory to produce the product. In this case, genes coding for human interferon are inserted into bacteria. Interferon is a substance that is naturally made by the body to fight infections and tumors. Bacteria produce the interferon, which is harvested and used as the active ingredient in Roferon-A.
Object consists of a sealed white cardboard box with red and black printing. Box contains one multiple-dose vial.
Location
Currently not on view
Credit Line
Hoffmann-La Roche, Inc.
product expiration date
1988-07-01
ID Number
1987.0786.01
accession number
1987.0786
catalog number
1987.0786.01
Object Name
biological
pharmaceutical
Physical Description
interferon alfa-2a, recombinant, 3 million IU per 0.5mL (drug active ingredients)
Measurements
overall: 2 11/16 in x 3 1/4 in x 2 in; 6.82625 cm x 8.255 cm x 5.08 cm
overall: 2 3/4 in x 3 1/4 in x 2 in; 6.985 cm x 8.255 cm x 5.08 cm
place made
United States: New Jersey, Nutley
See more items in
Medicine and Science: Medicine
Health & Medicine
The Antibody Initiative
Biotechnology and Genetics
Recombinant Pharmaceuticals
Science & Mathematics
Antibody Initiative: Monoclonal Antibodies
Data Source
National Museum of American History
Link to Original Record
Record ID
nmah_1000955